UIO stands for Quito Mariscal Sucr Airport. Codes like this one are often called IATA codes, a set of identifiers established by IATA (International Air Transport Association) that is widely used by airlines and the aviation industry.
Quito Mariscal Sucr (UIO), located 22.5 km from the city center, is the airport you fly into when you book flights to Quito.
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