₱43,078+ Cheap flights from Panama City

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/8. Fares are subject to change and may not be available on all flights or dates of travel. Click the price to replicate the search for this deal.
PTY — MNL
Apr 1 — Apr 81
1 adult
1 adult, Economy, 0 bags

Find flights from Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Panama City
Explore the most affordable flight options available from Panama City. Find the lowest fares based on data from user searches, with prices last updated on March 2, 2026.

Mon 8/1710:00 am
PTY
-
MNL
3 stops30h 55m
United Airlines
Tue 8/258:40 am
MNL
-
PTY
2 stops42h 34m
United Airlines
Deal found 2/28₱70,634
Thu 4/1612:56 pm
PTY
-
MNL
2 stops65h 04m
United Airlines
Wed 5/279:20 pm
MNL
-
PTY
1 stop26h 07m
United Airlines
Deal found 2/26₱74,297
Mon 4/137:55 am
PTY
-
MNL
2 stops49h 55m
EVA Air
Mon 4/206:50 pm
MNL
-
PTY
2 stops52h 37m
EVA Air
Deal found 2/27₱74,703
Wed 4/87:55 am
PTY
-
MNL
2 stops38h 45m
EVA Air
Wed 4/156:50 pm
MNL
-
PTY
2 stops28h 34m
EVA Air
Deal found 2/26₱76,099
Thu 4/1612:10 pm
PTY
-
MNL
2 stops40h 25m
EVA Air
Wed 5/276:50 pm
MNL
-
PTY
2 stops52h 37m
EVA Air
Deal found 2/27₱78,192
Sun 4/512:10 pm
PTY
-
MNL
2 stops45h 40m
EVA Air
Sat 4/185:45 am
MNL
-
PTY
2 stops41h 42m
EVA Air
Deal found 2/25₱79,471
Thu 3/1211:57 am
PTY
-
MNL
2 stops64h 53m
EVA Air
Tue 3/176:50 pm
MNL
-
PTY
2 stops28h 56m
EVA Air
Deal found 2/26₱80,343
Mon 8/1712:03 pm
PTY
-
MNL
2 stops45h 47m
EVA Air
Sun 8/236:50 pm
MNL
-
PTY
2 stops52h 37m
EVA Air
Deal found 2/28₱81,331

Find flights from Panama City within your budget

 
Find flights departing from Panama City that match your specified budget. Filter results by price range, allowing you to narrow down options and find flights that fit within your financial constraints. Please note that the search results are based on data from user searches, with fares last updated on March 2, 2026. In the last 7 days, Cheapflights users made a total of 411,093 searches

Fly to

Route

Depart

Return

Price

Panama CityManila

PTY - MNL

PTYMNL

Panama City Tocumen Intl

Thu 4/16

12:56 pm-7:00 pm

2 stops65h 04m

Manila Ninoy Aquino Intl

Wed 5/27

9:20 pm-10:27 am

1 stop26h 07m

₱74,297

Panama CityManila

PTY - MNL

PTYMNL

Panama City Tocumen Intl

Wed 4/8

5:53 pm-7:00 pm

1 stop36h 07m

Manila Ninoy Aquino Intl

Wed 4/15

9:20 pm-4:12 pm

2 stops31h 52m

₱107,957

Panama CityManila

PTY - MNL

PTYMNL

Panama City Tocumen Intl

Thu 4/16

7:55 am-5:55 am

2 stops33h 00m

Manila Ninoy Aquino Intl

Thu 4/23

8:40 am-10:27 am

1 stop38h 47m

₱107,957

Panama CityManila

PTY - MNL

PTYMNL

Panama City Tocumen Intl

Mon 4/13

9:55 pm-6:45 pm

1 stop31h 50m

Manila Ninoy Aquino Intl

Mon 4/20

8:55 pm-4:50 pm

2 stops32h 55m

₱111,794

Panama CityManila

PTY - MNL

PTYMNL

Panama City Tocumen Intl

Sat 3/28

5:51 pm-7:00 pm

1 stop36h 09m

Manila Ninoy Aquino Intl

Sat 4/4

9:20 pm-6:37 pm

2 stops34h 17m

₱120,398

Panama CityManila

PTY - MNL

PTYMNL

Panama City Tocumen Intl

Thu 3/12

5:51 pm-9:00 pm

1 stop38h 09m

Manila Ninoy Aquino Intl

Tue 3/17

11:25 pm-10:46 am

1 stop24h 21m

₱125,048

Panama CityManila

PTY - MNL

PTYMNL

Panama City Tocumen Intl

Wed 7/1

10:20 pm-7:10 pm

1 stop31h 50m

Manila Ninoy Aquino Intl

Fri 7/31

9:25 pm-6:30 pm

2 stops34h 05m

₱127,083

Panama CityManila

PTY - MNL

PTYMNL

Panama City Tocumen Intl

Wed 6/3

5:55 pm-7:00 pm

1 stop36h 05m

Manila Ninoy Aquino Intl

Fri 7/3

9:20 pm-6:37 pm

2 stops34h 17m

₱128,188

Panama CityManila

PTY - MNL

PTYMNL

Panama City Tocumen Intl

Thu 3/19

5:51 pm-9:00 pm

1 stop38h 09m

Manila Ninoy Aquino Intl

Wed 4/1

9:20 pm-10:27 am

1 stop26h 07m

₱139,059

Panama CityManila

PTY - MNL

PTYMNL

Panama City Tocumen Intl

Wed 4/15

10:20 pm-7:10 pm

1 stop31h 50m

Manila Ninoy Aquino Intl

Tue 4/21

9:25 pm-6:25 pm

2 stops34h 00m

₱142,082

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/26

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Best time to book a flight from Panama City

Have a flexible travel schedule? Discover the best time to fly from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Travel insights for flights from Panama City

Get recent, data-driven insights about flights from Panama City including ideal travel times, pricing trends, and more.

What is the cheapest month to book a flight from Panama City?

Currently, November is the cheapest month in which you can book a flight from Panama City (average of ₱42,439). Flying from Panama City in December will prove the most costly (average of ₱96,679). There are multiple factors that influence the price of a flight so comparing airlines, departure airports and times can help keep costs down.

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Direct flights from Panama

Book a non-stop flight from one of these other cities located in Panama.
Direct flights from Panama City

Related info for your journey

Access useful and relevant information related to your journey from Panama City. This can include details such as airport transportation, visa requirements, travel insurance, luggage regulations, and any other information that can ensure a smooth and hassle-free travel experience. Please note that the information is based on general guidance and may need to be verified with official sources. Data last updated March 2, 2026.

  • What are the most popular destinations to fly to from Panama City?

    For the current month, the most popular flights from Panama City are Bogotá, Bocas del Toro, David. Bogotá, Cancún, Cartagena are the most popular locations from Panama City year round.

  • What is the cheapest month to fly from Panama City?

    November is currently the cheapest month to fly from Panama City. At this moment in time December is the most expensive month. These prices are determined by multiple factors and booking in advance can help keep costs down if your schedule is not as flexible.

  • How does Cheapflights help users find flights from Panama City?

    Cheapflights helps you search for flights from Panama City via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

  • Why should you use Cheapflights to find cheap flight tickets from Panama City?

    By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights from Panama City.

  • Can Cheapflights find flights from Panama City with no change fees?

    Cheapflights does show flights with no change fees to all users. To see these options for flights from Panama City, users can toggle the no change fees filter when performing a flight search.

  • Can Cheapflights notify me if prices for flights from Panama City become cheaper?

    Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

See more FAQs

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City?

Cheapflights helps you search for flights from Panama City via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Panama City?

By finding flights from multiple airlines and providers at completely no cost, Cheapflights helps millions of users like you annually find the best flights from Panama City.

Can Cheapflights find flights from Panama City with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Panama City, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Panama City become cheaper?

Yes, Cheapflights has a feature called Price Alerts, which offers users the ability to be notified when flight prices change. Track prices for your flight from Panama City today and book when you’re ready!

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.